The research mainly focuses on integrative analysis of functional genomics datasets for complex human diseases

• to uncover the underlying molecular mechanism
• to identify genomic, proteomic and metabolic biomarkers
• to develop diagnostic and therapeutic kits
• to develop predictive mathematical and probabilistic models

Current researchs are:

• Systematic and integrative analysis of breast cancer and other associated diseases using transcriptome data and interactome networks (in collaboration with Penn State University College of Medicine)
• Using systems based models to uncover the disease network of psoriasis and its association with other autoimmune-related diseases (in collaboration with Istanbul Medeniyet University Faculty of Medicine)
• Integrative analysis of functional genomics datasets for infertility-associated woman diseases to identify genomic, proteomic and metabolic biomarkers
• Integration of transcriptome datasets with protein interactome network to analyze diabetes and its association with obesity and other diseases
• Comparative analysis of genome reprogramming during stem cell differentiation
• Statistical analysis and modeling of tumour response after Gamma Knife radiosurgery for intracranial metastasis cases (in collaboration with Marmara University Institute of Neurological Sciences)
• Investigation of the mechanism of action of endocrine disrupting chemicals through microarrays and systems biology approaches (in collaboration with Dep. of Bioengineering Microbial Ecology Research Group)