Systems Biomedicine

The research mainly focuses on integrative analysis of functional genomics datasets for complex human diseases

  • to uncover the underlying molecular mechanism
  • to identify genomic, proteomic and metabolic biomarkers
  • to develop diagnostic and therapeutic kits
  • to develop predictive mathematical and probabilistic models

Current researchs are:

  • Systematic and integrative analysis of breast cancer and other associated diseases using transcriptome data and interactome networks (in collaboration with Penn State University College of Medicine)
  • Using systems based models to uncover the disease network of psoriasis and its association with other autoimmune-related diseases (in collaboration with Istanbul Medeniyet University Faculty of Medicine)
  • Integrative analysis of functional genomics datasets for infertility-associated woman diseases to identify genomic, proteomic and metabolic biomarkers
  • Integration of transcriptome datasets with protein interactome network to analyze diabetes and its association with obesity and other diseases
  • Comparative analysis of genome reprogramming during stem cell differentiation
  • Statistical analysis and modeling of tumour response after Gamma Knife radiosurgery for intracranial metastasis cases (in collaboration with Marmara University Institute of Neurological Sciences)
  • Investigation of the mechanism of action of endocrine disrupting chemicals through microarrays and systems biology approaches (in collaboration with Dep. of Bioengineering Microbial Ecology Research Group)


This page updated by System Bioengineering on 12.01.2015 09:22:25