The research mainly focuses on:

• Extremophilic microorganisms to optimize production of industrially and medically important exopolysaccharides and enzymes via systems biology approaches.
• Chromohalobacter salexigens as a model organism for halophilic bacteria.
• Saccharomyces cerevisiae (Baker’s yeast) as a model organism for eukaryotic cells.

Research Topics are:

• Purification, characterization and recombinant production of levansucrase enzyme by Halomonas smyrnensis AAD6T
• Investigation of the fructose uptake system in Halomonas smyrnensis AAD6T to design strategies for enhanced levan biosynthesis
• Comparative genomics of halophilic bacteria
• Brevibacillus thermoruber as a microbial cell factory for exopolysaccharide production (in collaboration with Bulgaria Academy of Sciences)
• Reconstruction and analysis of comprehensive protein-protein and signal transduction networks in Saccharomyces cerevisiae and human
• Development of novel network metrics for topological analysis of complex biological networks
• Whole genome sequencing and genome annotation of levan producing Halomonas smyrnensisAAD6T
• Bioinformatics based metabolic network reconstruction of levan producing Halomonas smyrnensis AAD6T
• Genome-scale reconstruction and analysis of metabolic network for halophilic extremophile,Chromohalobacter salexigens DSM 3043
• System-based network approach to develop hypotheses for ethanol tolerant yeast strains (in collaboration with Boğaziçi University Department of Chemical Engineering)